This methylation profile is by now acquired at the MBL stage3 and remains somewhat stable after a while. Nonetheless, some CLL have intratumor variability in selected locations, which can alter the expression of various genes and aid tumor evolution.seventy one Of Observe, this variability is larger in U-CLL than in https://link-alternatif-mbl7716158.angelinsblog.com/31601550/5-easy-facts-about-link-alternatif-mbl77-described