This methylation profile is by now obtained on the MBL stage3 and remains rather steady eventually. Nevertheless, some CLL have intratumor variability in sure locations, which may change the expression of several genes and facilitate tumor evolution.seventy one Of Take note, this variability is greater in U-CLL than in M-CLL https://mbl7730639.prublogger.com/31591944/mbl77-can-be-fun-for-anyone