Remark: Barbiturates may well maximize adverse effects, like respiratory depression, made by harmful doses of TCAs. With therapeutic doses of TCAs, barbiturates boost metabolism and decrease blood concentrations of TCAs. pentobarbital will decrease the extent or impact of disopyramide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Not known. pentobarbi... https://veterinary-drug-for-eutha91234.worldblogged.com/40954007/indicators-on-euthanasia-sodium-pentobarbital-you-should-know