Epidural clonidine made use of as an adjunct to local anesthetics has 3 various mechanisms of motion. To start with, the stimulation of alpha-two-receptors during the dorsal horn lowers agony transmission. Secondly, clonidine might cause regional vasoconstriction that limits vascular elimination of local epidural anesthetics. Jun 10, 2024 · https://benjamini384znh9.jts-blog.com/profile