Butabarbital decreases effects of sufentanil SL by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Closely. Coadministration of CYP3A4 inducers may well lessen sufentanil amounts and efficacy, maybe precipitating withdrawal syndrome in patients that have developed Bodily dependence to sufentanil. Discontinuation of concomitantly utilized CYP3A4 inducers... https://miltonm741azv6.liberty-blog.com/profile